There is a picnic area overlooking Anza-Borrego Desert State Park near the Burnt Rancheria Campground, which is often said to deeply contrast the forest scenery along the route.

[3] Upon passing the settlement of Mount Laguna, the vegetation along the route mostly consists of dead trees devastated by the 2003 Cedar Fire.

The highway is part of the Juan Bautista de Anza National Historic Trail Auto Tour Route.

It crosses Interstate 5 and meets with CR S8 in Rancho Santa Fe at the intersection of Via de la Valle and Paseo Delicias.

About four miles (6.4 km) east on SR 76, CR S6 begins again as South Grade Road, which winds northward on Palomar Mountain.

Northward in Oceanside, El Camino Real passes under State Route 76 and ends just north at Douglas Drive.

San Marcos Boulevard intersects Rancho Santa Fe Road (CR S10) and continues eastward, crossing State Route 78.

Shortly thereafter, San Marcos Boulevard intersects with Twin Oaks Valley Road, which assumes the S12 designation after this junction.

Shortly afterwards, the road's name changes to East Vista Way, and continues northward outside the city limits into the unincorporated community of Bonsall.

Mission Road cuts north through Bonsall and passes the neighborhoods of San Luis Rey Heights and Winterwarm before entering Fallbrook.

These two streets run parallel to each other for several blocks; East Fallbrook Road (SR S15) begins at Mission and intersects Main.

Mission continues through San Marcos, passing under Twin Oaks Valley Road (County Route S12) without an intersection.

CR S15 continues east as Reche Road until it reaches its eastern terminus at the intersection with Old Highway 395, adjacent to Interstate 15.

It twists through a short but rugged and steep mountain range and continues northward as Pala-Temecula Road through rural San Diego County.

Shortly thereafter, County Route S16 widens to four lanes as it reaches the city limits of Temecula, where it becomes Pechanga Parkway.

The route consists of portions of several roads passing through the cities of Chula Vista and El Cajon, and the unincorporated communities of Bonita, Spring Valley, and Rancho San Diego.

Within El Cajon, CR S17 shares the same alignment as the former State Route 54, continuing north to Interstate 8 along Jamacha Road and 2nd Street.

However, all signs in Rancho San Diego (along Campo and Jamacha Roads) appear to have been removed except for the one heading east coming from the terminus of the freeway portion of State Route 94.

This makes it the second highway to become designated as a scenic road in Orange County, California, despite the impact from the Santiago Fire as part of the wildfires in October 2007.

The route is named "Coast Highway" in Oceanside, and comes to an end at Interstate 5 just south of Camp Pendleton.

The route travels northeast through portions of eastern Winterhaven, then immediately turns north through farmland, for 2.8 miles (5 km); (the continuation north exiting this route accesses the southern Chocolate Mountains, the western perimeter of the Little Picacho Wilderness, and Picacho State Recreation Area, a dirt road, sometimes rugged, wash-boarded and difficult).

Of note, the osprey have snag perches along the river route, and can be seen eating fish on pole tops, towers, etc.

1.5 miles (2.4 km) south of the Imperial Dam entrance, the Ferguson Lake Road and the Senator Wash access exits to the northwest.

CR S24 serves as a second access route to the Yuma Proving Ground, and also to the main housing and administration center of YPG.

County Route S25 (CR S25), commonly known as Chapman Avenue, is a 4.5 mile stretch of road in Orange, California, United States, that primarily travels east-west.

It runs from State Route 98 west of Mount Signal and north of the U.S.-Mexico border to Evan Hewes Highway (CR S80) in Seeley.

It runs from Interstate 8 near Felicity and west of Yuma, Arizona to the State Route 78 portion between Blythe and Brawley.

This portion of the highway travels 25 miles (40 km) east through Plaster City, Dixieland and Seeley to El Centro.

CR S80 then turns to the east along Main Street which takes it out of El Centro while SR 86 and Business I-8 continue south.

[29] For the short distance CR S80 runs concurrent with SR 86, it is part of the Juan Bautista de Anza National Historic Trail.