Cow and Chicken is an American animated comedy television series created by David Feiss for Cartoon Network.

The series focuses on the misadventures of two unlikely yet somehow biological siblings: the sweet-natured, dim, ecstatic, anthropomorphic Cow and her cynical older brother Chicken (both voiced by Charlie Adler).

The two are often caught in escapades with their flamboyant enemy, the Red Guy (Adler), a comical version of the Devil himself who disguises himself under various personas, usually to either scam everyone around or just for fun.

The humor and storylines depicted are often based on traditional childhood worries, anxieties, or phobias such as cooties or venturing into the girls' restroom, but enhanced comically.

[3] Years later, Feiss was called to submit ideas for What a Cartoon!, a series of various animated shorts from numerous creators and writers, created by Hanna-Barbera president Fred Seibert.

Supporting voices included Candi Milo and Dee Bradley Baker as Mom and Dad, and Dan Castellaneta and Howard Morris as Earl and Flem.

The second season segment "Buffalo Gals", first paired with "Cow and Chicken Reclining", was banned by Cartoon Network after they received one letter of complaint from a parent about the episode's visual and verbal innuendo about the titular biker group being lesbians.

The episode was also discussed on an installment of Rob Paulsen's Talkin' Toons special featuring Cow and Chicken creator David Feiss and voice actor Charlie Adler when an audience member asked why "Buffalo Gals" only aired once.

KJ Dell'Antonia of Common Sense Media gave the show three stars out of five, describing it as "if Ren & Stimpy starred in Monty Python..."[9] Cow makes a cameo in the beginning of The Grim Adventures of Billy & Mandy episode "Herbicidal Maniac" giving General Skarr fertilizer.

During the Mad episode "Once Upon a Toon", Cow and Chicken are among the classic cartoon characters reunited in a spoof of ABC's Once Upon a Time.

Weasel (with Michael Dorn reprising his role as Weasel for a speaking cameo) made cameo appearances as two of the Cartoon Network heroes that were summoned by Strike, and also Cow (as SuperCow) appears as one of the Cartoon Network heroes that Ben Tennyson (Ben 10) shapeshifts into.

The video game Cartoon Network Racing contains the episodes "Black Sheep of the Family" and "Child Star" (PS2 version only) as unlockable extras.

American releases Taco Bell promoted the series with a licensed kids meal featuring five toys from Cow and Chicken at 4200 restaurants beginning in February 1999.