Bonerama was formed in 1998 by trombone players Mark Mullins and Craig Klein, who, from 1990[1] up until late 2006, were also members of Harry Connick Jr.'s big band.
New Orleans drummers Russell Batiste, Stanton Moore, Doug Belote, Chad Gilmore, Terence Higgins, and Kevin O'Day have also been playing with Bonerama for periods of time.
Later, Charlie Wooton and Nori Naraoka electric bass replaced Matt Perrine before his return to the band in 2013.
On February 5, they released a joint EP with OK Go, entitled You're Not Alone, to raise money for New Orleans musicians displaced by the 2005 Hurricane Katrina.
After the departure of Rick Trolsen and Steve Suter in early 2009, trombonist Greg Hicks joined the band.