Creation of the World is a mosaic composition in the dome of the Chigi Chapel in Santa Maria del Popolo, Rome, designed by Raphael.

[1] Luigi da Pace signed and dated the work at the corner of the panel of Venus:[2] "LV[dovicus] D[e] P[ace] V[enetus] F[ecit] 1516" The central roundel represents God, the Father, surrounded by putti, effectively foreshortened in an impetuous gesture, harking back to Michelangelo, which seems to give rise to the entire motion of the universe below.

Eight mosaic panels show the Sun, the Moon, the starry sky and the six known planets as pagan deities depicted in half-length, each accompanied by an angel with colourful feathered wings.

A French engraver, Nicolas Dorigny created a series of plates depicting the mosaics in 1695 for Louis, Duke of Burgundy.

The blue background creates an optical illusion giving the impression of an architectural framework opening to the sky above the chapel.