[1] The genomes of this family are small (2.3–2.8 kilobases in length).

[2] The genomes are circular single-stranded DNA and encode rolling-circle replication initiation proteins (Rep) and unique capsid proteins.

[3][4] The viruses in this taxon were isolated from faecal samples from insects and vertebrates by metagenomic methods.

The family Smacoviridae is the sole member of the order Cremevirales and together with other families of CRESS DNA viruses is included within the phylum Cressdnaviricota.

[5] The family currently includes the following genera:[3][4] These viruses have single stranded genomes of 2.3–2.8 kilobases in length.