[1] Crisfield joined fellow Eastern Shore League charter members Cambridge Canners, Laurel Blue Hens, Parksley Spuds, Pocomoke City Salamanders and Salisbury Indians in beginning league play on June 12, 1922.
Joe Tagg of Crisfield won the Eastern Shore League batting title, hitting .329.
[3][4][5] The "Crabbers" moniker was in reference to local industry, as today, Crisfield is still noted as the greatest crab shipping point in the United States.
However, the Milford Sandpipers withdrew from the league in a dispute over an ineligible player and the Pocomoke City Salamanders folded during the season.
Jack Ryan again served as the Crisfield manager, as the Crabbers finished 24.0 games behind the first place Dover Senators.
Martin Breslin and Herb Armstrong served as managers, as Crisfield finished 9.5 games behind the first place Cambridge Canners.
The Crisfield Crabbers ended the 1926 Eastern Shore League season with a record of 63–21, to place first in the final standings.
With Mike Pasquella serving as manager, Crisfield finished 7.0 games ahead of the second place Salisbury Indians.
In league play, the Easton Yankees team was stripped of 34 wins due to roster violations and ended the 1926 season with an official overall record of 24–60.