Brisco received a Bachelor of Arts, cum laude, from Valparaiso University in 2002 and a Juris Doctor from the Notre Dame Law School in 2006.

From 2013 to 2017, she served as corporation counsel for the City of South Bend during Mayor Pete Buttigieg's Administration.

From 2018 to 2021, she served as a magistrate judge on the St. Joseph County Circuit Court in Mishawaka, Indiana.

President Biden nominated Brisco to the seat vacated by Judge Theresa Lazar Springmann, who assumed senior status on January 23, 2021.

[16] She became the first Black woman to sit as a judge on the federal court serving northern Indiana.