Franciscan High School, Baton Rouge, Louisiana, opened in August 2016, as Cristo Rey Franciscan High School and part of the Cristo Rey Network.

[3][4] On August 12–13, 2016, the school buildings were lost in the Great Flood of Baton Rouge.

In February 2018, the school returned to its original campus on St. Gerard Avenue in modular buildings.

In July 2022, the school cut its ties with Cristo Rey, operating with the sponsorship of the Franciscan Missionaries of Our Lady and within the Diocese of Baton Rouge, and was renamed Franciscan High School.

Cristo Rey Baton Rouge Franciscan High athletics competed in the LHSAA.