Cristuru Secuiesc (Romanian pronunciation: [ˌkristuru sekuˈjesk]; Hungarian: Székelykeresztúr, pronounced [ˈseːkɛjkɛrɛstuːr] ⓘ) is a town in Harghita County, Romania.

Cristuru Secuiesc lies on the Transylvanian Plateau, in the area where the river Goagiu flows into the Târnava Mare.

From 1933 to 1940, the town was renamed after I. G. Duca, the Prime Minister of Romania who was assassinated in December 1933 for his efforts to suppress the fascist Iron Guard movement.

After Soviet occupation, the Romanian administration returned and the town became officially part of Romania in March 1945.

[4] Demographic movements according to census data: In terms of religion, 46.02% of its inhabitants are Reformed, 35.99% are Unitarian, 14.27% are Roman Catholic, 2.33% are Romanian Orthodox.