Crookes Healthcare

It manufactures some of the best-known health remedies and over-the-counter drugs sold by British pharmacies.

[citation needed] By the 1960s it was making dosulepin, a tricyclic antidepressant (TCA), under the brand name Prothiaden.

In November 1960 it was bought by Arthur Guinness Son and Company in a joint-venture with Philips-Duphar (part of Philips Electrical Industries) of the Netherlands, who owned 40%.

In the 1980s its main competitor was the Beecham Group for OTC medicines, and with Warner-Lambert the three had about half of the market.

The 30-second TV advert, launched on 3 May 1989, used the voice instrumental section by Clare Torry (for which she was originally paid £150) of The Great Gig in the Sky.

Reckitt Benckiser bought Boots Healthcare International (BHI) for £1.9 billion in 2005, which required regulatory approval in early 2006.

The household-name products it makes are: In 2016 Nurofen was one of the biggest selling branded over-the-counter medications sold in Great Britain, with sales of £116.8 million.