Cross Keys is an unincorporated community located in Rockingham County, in the U.S. state of Virginia.

[1] On June 8, 1862, it was the site of the Battle of Cross Keys, a Confederate victory in Jackson's Valley Campaign during the American Civil War.

The climate in this area is characterized by hot, humid summers and generally mild to cool winters.

[2] Ananias Davisson, the publisher of the first Southern shape note tunebook, the Kentucky Harmony (1816), is buried in the Cross Keys cemetery.

Davisson was from the Shenandoah Valley, but many of the songs were collected during trips to Kentucky and Tennessee.