The University of Uyo inherited students, staff, academic programmes and the entire facilities of the then University of Cross River State established by Cross River State in 1983.
[5] The Office of the Vice-Chancellor, Deputy Vice-Chancellor and the Bursar are all located in the Calabar Campus, considered the main campus of the Institution, which is located in Calabar South Local Government Area of Cross River State in Southern Nigeria.
[6] The University was established in 2002 by the then Governor Donald Duke by merging three higher institutions: The Polytechnic of Calabar, The College of Education, and Ibrahim Babangida College of Agriculture.
[7] It offers degree courses at undergraduate and post graduate levels.
[9] Faculties and Departments at the University of Cross River State includes;