Cruzeiro Esporte Clube, commonly referred to as Cruzeiro de Rondônia, or simply Cruzeiro-RO, was[note 1] a Brazilian professional football club based in Porto Velho, Rondônia.

Their activities are currently closed due to financial difficulties.

Cruzeiro-RO has last played in a professional match in May 2010.

[3] They competed in the Copa Norte in 1999, finishing as the fourth place of the cup after being defeated in the semi-finals by São Raimundo of Amazonas state.

Cruzeiro Esporte Clube played their home games at Estádio Aluízio Ferreira.