She is known for her work in advertising, her New York Times bestselling book, for being an early investor in Uber and Blue Bottle Coffee through Lowercase Capital, and for her philanthropy.
Sacca attended the Edmund A. Walsh School of Foreign Service at Georgetown University.
Through the early 2000s, Sacca worked in advertising, serving as art director to clients such as Audi, Intel, Barclays, HBO, Sprint, and Napster.
[17][18] In 2019, Sacca was appointed to the Board of Trustees of the Cooper Hewitt, Smithsonian Design Museum.
The organization describes itself as dedicated to furthering a "more just and beautiful world" through the efforts of creative leaders.