She is known for her scream queen roles in horror films such as Children of the Corn: Revelation (2001), Final Destination 3 (2006), Black Christmas (2006), and Wrong Turn 2: Dead End (2007).

Lowe was born Yan-Kay Lo in Vancouver, British Columbia to a Scottish mother and Chinese father[2] from Hong Kong.

Lowe went on to guest star in several popular television shows like Masters of Horror, Psych, Supernatural, Stargate: Atlantis, The L Word, plus many more.

Also in 2008, Lowe was cast in supporting roles for the films Yeti: Curse of the Snow Demon, Poison Ivy: The Secret Society and Center Stage: Turn It Up.

[5][6] In 2014, Lowe was cast as Rita Haywith in the Hallmark series Signed, Sealed, Delivered, which aired for one season in 2014 before becoming successive television films.