Cubosome

Cubosomes are liquid crystalline nano-structures formed from the cubic phase of lipids, such as monooleate, or any other amphiphilic macromolecules with the unique property to be dispersed into particles.

Nano-vehicles are generated from a self-assembled lipid mixture and studied by means of high-resolution cryogenic transmission electron microscope (cryo-TEM).

This property is called isotropicity which gives cubosomes the ability to be used in biological tissues which are highly structured and typically have different diffusion coefficients along different directions (anisotropic).

Because of advantages such as the unique structure of the cubic phase and its resemblance to biological membranes as well as biodegradability of lipids, cubosomes are a great tool for drug delivery system.

Capability to encapsulate hydrophilic, hydrophobic, and amphiphilic substance, being simple to prepare, and all the aforementioned qualities give cubosomes a property that can be used in controlled transport applications as drug delivery vehicles.