Cuckoo is a small unincorporated community in Louisa County, Virginia, United States.

The Cuckoo Tavern stood nearby, which in 1781 was the beginning of Jack Jouett's ride to warn the Colonists of the arrival of Banastre Tarleton's British cavalry (similar to Paul Revere's Ride).

There was also a large house named Cuckoo built in 1819 for Henry Pendleton on the former property of William Overton Callis.

[3] Shirley Ann Jackson, American nuclear physicist and President of Rensselaer Polytechnic Institute, has familial ties to Cuckoo.

[4] On Tuesday August 23, 2011, at 1:51 PM ET a magnitude 5.8 earthquake was recorded[5] 2.4 mi (3.9 km) SW of Cuckoo on the western bank of Indian Creek.