Despite primarily performing reggae music, Cultura Profética has experimented with genres such as bossa nova, tango, jazz, and salsa.

Lyrically, the group discusses socio-political and ecological issues including Latin American identity and environmental concerns, as well as interpersonal relationships and love.

After gaining popularity in Puerto Rico as a cover band, Cultura Profética began performing original music and released its debut album, Canción de Alerta, in 1996.

In recent years, Cultura Profética has released the singles "Saca, Prende y Sorprende" (2014), "Le Da Igual" (2015), and "Musica Sin Tiempo" (2017).

"[2] Group members Boris Bilbraut, Willy Rodríguez, Eliut González, Juan Costa, and Ivan Gutiérres began jamming together in 1996, bonding over a shared interest in reggae music, particularly Bob Marley.

[2] The band's first album, Canción de Alerta (1998), was recorded in the Tuff Gong studios at Jamaica with Errol Brown, frontman of Hot Chocolate and Bob Marley's sound engineer.

[4] The record discusses a number of social issues in Puerto Rico, including the importance of acknowledging the island's African influence.

[10] After the release of the tribute album, Cultura Profética toured extensively through Latin America and expanded its fan base, particularly in Argentina.

[10] Before the album's official release, the band posted songs on the internet, including "La Complicidad", which became a radio hit in Puerto Rico.

Guitarist Eliut Gonzalez remarked that the band aimed to shift discussion to "the good things in the world", explaining that "We know that people need help, and that behind every revolution or movement, there is love.

[12] The group's single "Saca, Prende y Sorprende", released in 2014, pays homage to Jamaican deejay and rapper Super Cat and advocates for the legalization of marijuana.

[11] Gonzalez describes the band's upcoming record as "very different" from La Dulzura, noting that the group began working on new material while on tour approximately a year after the album's release.

[15] In March 2020, Cultura Profética collaborated with American singer John Legend and Mexican-American mariachi group Flor De Toloache on the single "Quisiera".

"[10] Leila Cobo of Billboard observed elements of jazz in the single "La Complicidad," additionally describing it as "more mellow rock than reggae.

Canción de Alerta contains the song "Por qué cantamos," an adaptation of Uruguayan writer Mario Benedetti's poem of the same name.