The album features guest appearances from Drake, Cardi B, Polo G, Future, Justin Bieber, Juice Wrld, Pop Smoke, and YoungBoy Never Broke Again.

[6] Quavo spoke to Billboard in March 2020, announcing the trio's decision to hold off on releasing Culture III, explaining that it was largely due to their inability to properly roll out the album once social distancing rules went into effect in most states in the United States of America.

[17] Robin Murray of Clash praised the album, stating, "A huge undertaking, Culture 3 is marked by its dense array of sonic reference points.

It's a huge record, a panoramic thriller that places three incendiary MCs against a digital orchestra – an ambitious, lavish, and extraordinarily successful release".

[20] Reviewing the album for NME, Sam Moore stated, "Culture III is more focused than its exhausting 24-track-long predecessor, but a stricter edit here could've enhanced the experience even further".

But it's those occasional reaches outside the tried and true – be it beats or collaborators – that make for a more compelling listen, even if they don't always smack the mark".

[21] Ben Brutocao of HipHopDX said, "The beats are pleasant to excellent, the raps are practiced yet dry, and the trio that has come so far finds itself not moving at all".

[23] AllMusic critic Neil Z. Yeung said, "While the set is a bit of a chore at 19 tracks (24 on the deluxe version), it's still not as bloated as Culture II.

[19] Writing for Pitchfork, Paul A. Thompson stated, "Like its predecessor, Culture III can become a slog, and at times seems shoddily constructed, its commercial ambitions ill-considered and to the album's detriment.

[26] In a mixed review, Slant Magazine's Charles Lyons-Burt stated, "In all the excess, one is nonetheless left wanting more—better fleshed-out personas or a glint of a new stylistic direction rather than a doubling down on committee-tested beats and a formulaic approach.

[28] Culture III debuted at number two on the US Billboard 200 chart, earning 130,000 album-equivalent units (including 22,000 copies as traditional album sales) in its first week.