[2] In the early years of his professional career, Seckler accompanied his brothers, George and Duard, with tenor banjo and vocal harmonies in their group, "The Yodeling Rangers."
[2] Seckler continued to enjoy success on the Bluegrass touring circuit, and in 1949 joined Lester Flatt, Earl Scruggs, and the rest of the Foggy Mountain Boys band.
In this same year, Bill Monroe released a song called "Traveling This Lonesome Road," which Curly and his wife Juanita had written, but hadn't copyrighted.
After leaving the Stanley's, Curly started a new group, called "The Cumberland Mountain Boys", with Jim & Jesse McReynolds to replace Flatt & Scruggs's position at the Kentucky Barn dance in Versailles, KY.
[6] His release of "Sixty Years of Bluegrass with My Friends" in 2005 on the Copper Creek label solidified Seckler's place as one of the pioneers of the genre and steward of customs and traditions.
Throughout his career, Seckler played with Jim and Jesse McReynolds, Mac Wiseman, the Stanley Brothers, the Nashville Grass, Doyle Lawson, and many others.