The arc centers on a human bomb exploding in San Francisco's Union Square, covering dozens (including Jubilee) in vampire-converting blood.

It then becomes the mission of the X-Men to track down Dracula's son Xarus, now "Lord of the Vampires", even if that means enlisting vampire-hunter Blade.

[4] There is also a four-issue miniseries that links in with "Curse of the Mutants", Namor the First Mutant by Stuart Moore,[5] as well as a two-issue miniseries X-Men vs. Vampires by various creators and a number of one-shot issues: Blade by Duane Swierczynski,[6] Storm and Gambit by Chuck Kim,[7] and Smoke and Blood by Simon Spurrier.

A four-issue miniseries by Kathryn Immonen and Phil Noto that ties into the storyline, called Wolverine and Jubilee: Cursed,[8] started in January 2011.

Xarus' allies in the Mystikos Sect managed to invent a special device that can block the frequencies of light that are harmful to vampires.

Alyssa secretly slips one of the light-deflecting pendants to Janus, which enables him to escape after the Claw Sect betray him to Xarus.

[10] Blade arrives in San Francisco to assist the X-Men in capturing a vampire specimen for the X-Club.

Much later, while the X-Men gather to discuss the death of Dracula and learn who the new Lord of Vampires is, Kavita Rao is seen checking on Jubilee, only to be attacked.

[11] While underwater, Namor has an encounter with a race of Atlantean vampires and is tasked with retrieving the head of Dracula.

[15] As X-Club members Madison Jeffries, Kavita Rao, and Doctor Nemesis work on a cure for the vampirism, their test subject escapes and the lab goes into lockdown.

But unknown to him, Nemesis has injected him with nanobots to shut down his healing factor, as Cyclops had anticipated that he might be bitten and turned before they could reactivate it.

But Xarus will have none of it, declaring that he will take Utopia today, raise a flag over it, stand over Wolverine's bones and drink Cyclops' blood.

Whereas Cyclops wants nothing more to do with the Vampire Nation, Blade does not see eye-to-eye with him and charges at Dracula, only to knocked unconscious with an optic blast.