Certain places feature prominently in the Marvel Universe, some real-life, others fictional and unique to the setting; fictional places may appear in conjunction with, or even within, real-world locales.
Many Marvel Comics stories are set in New York City, where the publishing company is based.
[1] New York is the site of many places important to superheroes: New York is a center of industry, serving as the headquarters for a few Marvel companies: The following prisons are located in outer space: The Earth of Marvel's main continuity (or "Earth-616") has contained a number of fictional hidden native humanoid races.
Many of these races are genetic offshoots of Homo sapiens or a related ancestor.
The methods to create these beings vary from scientific to magical and their creators from aliens to humans to demons.