Cyborg Commando introduced the "10X" dice-rolling mechanism: To determine the success or failure of a skill challenge or combat, the player rolls two 10-sided dice and multiplies the results.

As game critic Rick Swan noted, "Its difficult rules and narrow scope severely limited its appeal.

Stewart Wieck reviewed Cyborg Commando in White Wolf #9 (1988), rating it an 8 out of 10 and stated that "This is not a game for the beginner.

Swan concluded by giving the game an excellent rating of 3.5 out of 4, saying, "For those up to the challenge, it's definitely worth checking out — Cyborg Commando is hardcore role-playing at its best.

"[6] Writing 27 years after Cyborg Commando's publication, game historian Shannon Appelcline noted the game's complex rules and the lack of connection to Gygax's D&D fans, and wrote, "As a result of these various factors, Cyborg Commando is today seen as one of the biggest flops in the industry.