She worked for subsidiaries of Merrill Lynch in the United Kingdom and the Shin Kong Group in Taiwan before she was appointed to the Legislative Yuan in 2022.

[12] On 24 November 2023, Taiwan People's Party chairman Ko Wen-je named Wu as his running mate for the 2024 presidential election.

[13] Despite controversy regarding her citizenship, on 4 December, all presidential and vice-presidential candidates were found and declared eligible to run for election, including Cynthia Wu.

[15] In September 2013, Wu noticed that Lin, who suspected her of infidelity, had installed a GPS tracking unit in her car, and subsequently filed for divorce.

[18][19] Although a second ruling in 2019 granted the divorce, Wu stated that the decision would deny her the experience of motherhood, as embryos that had been artificially inseminated during her marriage to Lin would be destroyed.