[citation needed] It produces a venom containing numerous compounds capable of blocking neurotransmitters, including neurotoxic peptides called hainantoxins.

Cyriopagopus hainanus resembles C. schmidti, but can be distinguished by its dark black-brown body and the longer "thorns" on the forward-facing (prolateral) side of the maxillae.

The spider remains in its burrow during the day, emerging only at night to catch prey, mainly large insects.

[2] Its venom is the subject of toxicology research, and while the effects of this spider's bite on humans are not well documented, it is frequently lethal in small doses to laboratory animals such as mice and rats.

The venom is a complex neurotoxin, containing numerous compounds capable of blocking neurotransmitters,[4] including neurotoxic peptides called hainantoxins.