Cyrrhus (/ˈsɪrəs/; Greek: Κύρρος, romanized: Kyrrhos) is a city in ancient Syria founded by Seleucus Nicator, one of Alexander the Great's generals.

Other names for the city include Coricium, Corice, Hagioupolis, Nebi Huri (Arabic: نبي هوري), and Khoros (حوروس, Ḳūrus).

The site of the city is marked by the ruins at Khoros, 20 km from Azaz, Syria, standing near the Afrin Marsyas River, a tributary of the Orontes, which had been banked up by Bishop Theodoret.

By the 1st century AD, it had become a Roman administrative, military, and commercial center on the trade route between Antioch and the Euphrates River crossing at Zeugma, and minted its own coinage.

[3] In the 6th century, the city was further embellished and strengthened by Byzantine Emperor Justinian, who oversaw work that only added to the Cyrrhus' already incredibly formidable defenses.

Remains in Cyrrhus include two Roman Bridge s in working order, a dilapidated theatre outside the town and foundations of a Basilica church and some city fortifications.

Syros became a frontier city after the separation of Asia Minor from the Seleucid state, following the Treaty of Apamea in 188 BC, which lost its civilian importance and became a center for assembling armies and securing the strong soldiers of the kings of Antioch.

[11][12][13] A magnificent basilica held the relics of Saints Cosmas and Damian, who had suffered martyrdom in the vicinity about 283, and whose bodies had been transported to the city, whence it was also called Hagioupolis.

Many holy personages, moreover, chiefly hermits, had been or were then living in this territory, among them Saints Acepsimas, Zeumatius, Zebinas, Polychronius, Maron (the patron of the Maronite Church), Eusebius, Thalassius, Maris, James the Wonder-worker, and others.

No longer a residential bishopric, Cyrrhus is today listed by the Catholic Church as a titular see,[22] in two different rite-specific traditions, in the apostolic succession of the Byzantine archdiocese.