Cytochemistry

[1] The term is also used to describe a process of identification of the biochemical content of cells.

Cytochemistry is a science of localizing chemical components of cells and cell organelles on thin histological sections by using several techniques like enzyme localization, micro-incineration, micro-spectrophotometry, radioautography, cryo-electron microscopy, X-ray microanalysis by energy-dispersive X-ray spectroscopy, immunohistochemistry and cytochemistry, etc.

[2] Freeze fracture enzyme cytochemistry was initially mentioned in the study of Pinto de silva in 1987.

[4] The combination of immunocytochemistry and freeze fracture enzyme technique, research can identify and have a better understanding of the structure and distribution of a cell membrane.

The work by Moller and Holter in 1976 about endocytosis which discussed the relationship between a cell's structure and function had established the needs of cytochemical research.