[8] Their ancestor, a grandson of Gediminas, the Grand Duke of Lithuania, became known with his baptismal name Constantine (c. 1330−1390) - he became a Prince of Chortoryisk in Volhynia.

[10] The founding members were culturally Ruthenian and Eastern Orthodox; they converted to Roman Catholicism and were Polonized during the 16th century.

He married Isabella Morsztyn, daughter of the Grand Treasurer of Poland, and built "The Familia" with their four children, Michał, August, Teodor and Konstancja.

The family became known and powerful under the lead of brothers Michał Fryderyk Czartoryski and August Aleksander Czartoryski in the late Polish–Lithuanian Commonwealth of the 18th century, during the reigns Augustus II the Strong (King of Poland, 1697–1706 and 1709–1733) and Stanisław I Leszczyński (King of Poland 1704–1709 and 1733–1736).

The descendants of Prince Konstanty Adam Czartoryski live to this day in Poland and have their representatives in the Confederation of the Polish Nobility.