DEFB105A

24590877674ENSG00000186562ENSMUSG00000043787Q8NG35Q8K4N3NM_152250NM_152802NP_689463NP_690015Beta-defensin 105 is a protein that is encoded by the DEFB105A gene in humans.

[5][6][7] Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils.

All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions.

Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster.

This duplication results in two identical copies of defensin, beta 105, DEFB105A and DEFB105B, in tail-to-tail orientation.