They are known for their mashups of popular songs turned into electronic dance music.

The project started in 2003 after the meeting of young producers Luca Emanuele Ventrafridda (aka Luca Ventafunk) and Massimiliano Garino (aka Max Aqualuce), in Bliss Corporation,[1] an Italian label famous for the project of Eiffel 65 in the late 1990s.

It was only after a few years and several tracks together that they initiated the common project "DJs from Mars".

With the help of their American manager Jason Nevins, DJs from Mars produced official remixes for multiple artists, including Sean Paul, Pitbull, Sophie Ellis Bextor, Dirty Vegas, Fragma, Ciara, Coolio, and Ennio Morricone.

Famous for wearing cardboard boxes on their heads while playing live, they performed at a number of night clubs and events over the world including Europe, USA, Brazil, Dominican Republic, Canada, and China.