[5] DZBB marked its inaugural broadcast, as the station's static-marred signal was wafted on the air for the first time on March 1, 1950, by Robert "Uncle Bob" Stewart, in a small office space in Calvo Building, Escolta, Binondo, Manila, with mostly second-hand equipment and an old, surplus radio transmitter.

It was also a pioneer with trendsetting shows such as Camay Theater of the Air, Cathay Broadcasting, Lovingly Yours, Helen, Kahapon Lamang, Tawag ng Tanghalan, Newscoop, and Kwentong Kutsero.

Two years later, due to changes in media ownership laws, Channel 7, DZBB and their other sister provincial radio and television stations were eventually sold to the triumvirate of Gilberto Duavit Sr., Menardo Jimenez and Felipe Gozon.

Rafael "Paeng" Yabut, Bobby Guanzon, Lito Villarosa, Rene Jose, Rey Pacheco, Raul Virtudazo, Jimmy Gil, Arman Roque, Rose "Manang Rose" Clores, German Moreno, Inday Badiday, Helen Vela, Augusto Victa, Manolo Favis, Henry Jones Ragas and Pol Caguiat were the personalities of the Bisig Bayan years.

In 2014, DZBB kept its winning streak in Mega Manila as it continued to lead rival stations in ratings, according to data from Nielsen Media Research.

[9] On April 24, 2017, DZBB officially launched its new logo, its first ever jingle for the station and its newly renovated radio booth, as well as the relaunch of Dobol B TV, after almost five years of hiatus on television.

In 2020, DZBB temporarily suspended its regular programming, especially during overnight hours, in line with the enhanced community quarantine imposed by former President Rodrigo Duterte due to the COVID-19 pandemic, which replaced them with news updates and hookup to sister station DWLS.

On some occasions, DZBB would also air live and exclusive blow-by-blow boxing coverage, especially during Manny Pacquiao's fights (alongside Super Radyo stations nationwide).

On May 7, 2023, DZBB added a simulcast of the investigative public-service show Resibo: Walang Lusot ang May Atraso, also from GMA Network.