Daisy Hill is one of the principal stations that lie on the Manchester-Southport Line, between Southport and Manchester.

The station is located 14 miles (23 km) west of Manchester Victoria with regular Northern services to these towns as well as Salford, Swinton and Hindley, with onward trains to Kirkby and Southport.

These tracks were removed in early 1966, leaving only the lines adjacent to the central island platform.

This is accompanied by pre-recorded automated announcements heard via speakers located both on the platform and in the booking hall.

Daisy Hill village, with its few shops, church and cricket ground is five minutes by foot (turn left outside the station).

The station's island platform remains totally inaccessible (even with assistance) to wheelchair users, as the only means of access is via a staircase,[2] however works are being carried out at the station for a lift to be installed as part of Northern's Access for All scheme.

The regular daytime service to Southport ended at the start of the winter 2019 timetable, with passengers now having to change at Wigan (except for a few peak-period and late evening trains).

In Autumn 2021, the service was reduced back to two per hour all day - one to Blackburn via Todmorden and the other to Leeds eastbound, with one each to Kirkby and Wigan North Western westbound.

An extra train operates from Daisy Hill during weekday peak times, one train per day calling at all stations between Wigan North Western and Manchester Victoria during the morning and returning in the opposite direction during the evening.