Her art used a range of mediums, including assemblage, collage, installation, audio, video, photography, new genres, writing, speaking, and performance.

Ayo earned a Bachelor of Arts degree in 1990 from Brown University with a double concentration in Public Policy and American Civilization.

Her work displayed influences from artists such as Adrian Piper, Yoko Ono, On Kawara, and William Pope.L.

Her work utilized assemblage, collage, photography, installation, audio, video, new genres, writing, speaking, and performance.

Her 2000 show The Little Black Dress Project and accompanying performance Take it Off explored the notion of the reality of women's lives juxtaposed with the wardrobe of fashion conformity.

Performed in Portland, Boulder, Syracuse, and at the 2004 International Geographic festival at Galerie SAW in Ottawa, Canada.

In 2007 Ayo created an interactive guidebook titled You Can Fix Racism by asking the members of her email list for their top ten solutions to improve race relations.

It was granted a 2005 Honorable Mention in the Outstanding Book Awards from the Gustavus Myers Center for the Study of Bigotry and Human Rights.

[8] Ayo's stories for public radio explored the process of art making, social issues, environmental consciousness, her own identity transformations, and classical music.

[9] Her story “Living Flag” received a 2005 Silver Reel Award from the National Federation of Community Broadcasters.

[10] The July 2008 issue of Redbook magazine reported that after a string of terrible on-line dates, ayo redirected her energies to "eco fitting" her house.