A 1923 graduate of Santa Ana High School, Dana joined the crews of the steamer W. M. Irish and the S. S. Carenco, traveling to the Eastern United States and Morocco, Egypt, Greece, Italy, Cyprus and Syria in 1924–1925.
In August, they embarked on what became a three-year, 16,000 mile voyage in their homemade, sixteen-foot canoe, the Vagabunda, from Southern California down the Pacific coasts of Mexico, Guatemala, and Costa Rica, and culminated in their crossing of the Panama Canal in September 1936.
Their second book, Quest for the Lost City (1951), detailed their continued adventures in the 1940s and was the basis for a feature-length film of the same name produced by Sol Lesser and released by RKO Pictures in 1954.
Having made the seaside village of Corona del Mar their home base during their years of adventure travel, the growing population explosion in Orange County in the postwar era prompted the Lambs to move to the former mining town of Hillsboro, in the southwestern mountains of New Mexico, in 1962.
The ensuing years for Dana Lamb were not idle, as he had to deal with the ramifications of a disastrous flood in Hillsboro in September 1972 and traveled to Micronesia in 1975-1976 before his death on June 11, 1979.