Gibson graduated sixth out of 212 students in his high school class, and was a member of the National Honor Society.

Gibson was named the Big 12 Freshman of the Year after his first season, averaging 14.2 points, 3.6 rebounds and 3.9 assists per game.

[1] On June 7, 2006, Gibson announced his decision to forgo his two remaining years of college eligibility and enter the NBA draft.

Cavs coach Mike Brown gave Gibson his first place in the starting line-up on December 6, 2006, against the Toronto Raptors.

Gibson had his first big playoff opportunity in game 3 of the 2007 Eastern Conference Finals against the Detroit Pistons.

He also grabbed 2 rebounds, blocked 1 shot, and had an important steal from Tayshaun Prince late in the fourth quarter.

However, Daniel Gibson struggled defensively guarding Tony Parker who averaged 24.5 points a game and a finals MVP Trophy.

Gibson said missing game 7 of the Boston series still haunts him: "I've had a lot of sleepless nights just wondering where I could have helped the team.

"[11] Gibson was selected to participate in the Rookie Challenge (Sophomore team)[12] and the Three-point Shootout during the 2008 NBA All-Star Weekend in New Orleans.

During the first half of the Rookie Challenge, Gibson tied the record for total three-pointers made, despite not being a starter in the game.

He later set the record in the second half with eleven total three-pointers, finishing the game shooting 11–20 from beyond the arc.

[1] The couple's 2011 wedding was filmed and aired on their BET reality TV series Keyshia & Daniel: Family First on October 9, 2012.

On July 29, 2013, Gibson turned himself in to New Orleans police to face a charge of second degree battery related to an incident that took place earlier that month.

His attorney declined to comment on the matter, but police said Gibson struck a man, breaking his jaw, in an altercation at a local night club.

[18] After the 2012–2013 season, injuries to his foot and ankle, grieving his grandmother's death, and a lengthy divorce, Gibson began suffering from depression and anxiety, and began writing music to cope with the issues, contrary to rumors that he intentionally was starting a rap career.

[19] In 2017, he toured internationally with other retired NBA players as a part of the Champions Basketball League [20] and he and Cole were featured in the VH1 reality TV show Love & Hip Hop: Hollywood.