He was then appointed the Bishop of the Roman Catholic Diocese of Matadi from 2010 until his early resignation on 6 March 2021, due to declining health.

[1] Born on 19 October 1953[2] in Kinkosi,[2] present-day Kongo Central province, Mayi was ordained as a Catholic priest in the Archdiocese of Kinshasa in April 1980.

[1] Mayi later served as the Apostolic Administrator of the Archdiocese of Kinshasa from January 2007 to February 2008 when Bishop Laurent Monsengwo Pasinya was elevated as a Catholic Cardinal.

[1] Bishop André Giraud Pindi was appointed as acting Apostolic Administrator of Matadi until a permanent successor could be selected.

[1][2] On 11 December 2021 Bishop Emeritus Nlandu Mayi celebrated a mass at the Tumba Dia Zayi Institute, a school operated by the De La Salle Brothers.