She was one of the original cast members of the long-running soap opera Shortland Street, though she is also known for her role as the Amazon Ephiny in the television series Xena: Warrior Princess, Cynthia Ross in The Cult, and Shota in Legend of the Seeker.

[3] She portrayed notorious Sydney underworld figure Kate Leigh in Underbelly: Razor, and doctor Rory Finch in Jack Irish.

[13] Cormack, alongside Wentworth cast member Nicole da Silva, started the production company Four One One,[14] and together they produced their first play Whose Afraid in 2022.

[16][17] In 2018, Cormack while working alongside aid agency ChildFund, helped build a water tank that would supply villages in Uganda.

[21] In an interview with LOTL magazine in 2016, Cormack said that she had had long-term relationships with both men and women, and indicated that she prefers to avoid applying labels to patterns of sexuality.