[1] He made his Russian Premier League debut for Arsenal on 4 July 2020 in a game against FC Dynamo Moscow, replacing Aleksandr Lomovitsky in the 83rd minute.

[citation needed] On 1 November 2021, he signed a 4.5-year contract with FC Spartak Moscow beginning on 1 January 2022.

Khlusevich started the 2023-24 season by scoring two goals, including one in stoppage time, to achieve a 3-2 victory over FC Orenburg on 23 July 2023.

Khlusevich was called up to the Russia national football team for the first time for a friendly against Kyrgyzstan in September 2022.

[5] A Ukrainian citizen by birth, he acquired citizenship of Russia in 2014 after the annexation of Crimea from Ukraine.