Formed in 1987 in Lodi, New Jersey, the group early on became a unique voice in the rock scene, playing a bluesy, doom-laden[2][3][4] metal with Glenn Danzig crooning in the style of Roy Orbison and Elvis Presley.

After a major hit with a live version of its 1988 song "Mother", the band experimented with industrial music but later returned to heavy metal.

[8] The first release from the band, minus Eerie Von, was the song "You And Me (Less than Zero)" from the Less than Zero soundtrack and credited as Glenn Danzig & The Power and Fury Orchestra.

The live version of "Mother", a song from the first album, became popular on album-oriented radio stations while its music video received considerable attention on MTV-programmed shows such as Beavis and Butt-Head,[15] Headbangers Ball[16] and 120 Minutes.

[18] The renewed popularity of "Mother" not only helped raise Danzig's profile in the music industry, but also saw the band starting to perform at larger venues such as arenas and amphitheaters, which included headlining US tours with bands like White Zombie, Kyuss, Type O Negative, Godflesh and then-emerging acts Korn and Marilyn Manson, as well as opening for Metallica and Black Sabbath.

Amid accusations of unpaid royalties and broken promises, Danzig's relationship with Rubin deteriorated and the band left the record label.

Biscuits was replaced by Joey Castillo, who made his first public appearance as a member of Danzig at an in-store signing the day of the fourth album's release.

Although the band had toured successfully with its new drummer during the fall and winter of 1994–95, by the spring of 1995 Danzig was actively seeking a new guitarist, with Pepper Keenan and Dez Cadena considered possible replacements.

Samhain opened for Danzig for six weeks during the tour and consisted of Steve Zing and London May switching between bass and drums.

By 2000, Danzig's lineup had stabilized with the addition of guitarist Todd Youth and bassist Howie Pyro, both veterans of the New York City punk scene.

Soon after the album's release, Danzig undertook the Blackest of the Black tour across the US, replacing Circle of Snakes drummer Bevan Davies with Johnny Kelly (of Type O Negative).

This tour debuted Kenny Hickey (of Type O Negative) as the band's new guitarist, while the East Coast dates saw the addition of former Samhain member, Steve Zing on bass.

Danzig has also stated that he plans to record a dark blues album with either Jerry Cantrell or Hank Williams III.

The show was notable for featuring a special appearance by Michale Graves who, along with Doyle and Dr. Chud, performed several songs by the reformed version of the Misfits.

In January 2011, Danzig was announced for the 2011 Download Festival at Donington Park, England, alongside bands including Rob Zombie, Alice Cooper, and System of a Down.

[32][33] On September 4, 2015, Danzig released a 7" vinyl single, limited to 500 copies, of "Devil's Angels" to promote the covers album, Skeletons.

[35] In July 2016, the band's official Facebook page confirmed that Danzig Sings Elvis was finished; however, the album was not released until April 24, 2020.

"[38] In May 2023, Glenn Danzig unveiled a series of live performance dates in celebration of the 35th anniversary of the self-titled debut album.