Through researching his genealogy, Little discovered he is a distant descendant of notable figures such as Alfred the Great and William the Conqueror, as well as the Australian bush wrangler Daniel Priest.
[3] While at Manchester Polytechnic, he wrote his dissertation about Coronation Street and Tony Warren who became his mentor and insisted the producers gave him a job.
He created the characters Sean Tully, Archie Shuttleworth, Bev Unwin and Eric Gartside who was played by Peter Kay.
He worked closely with Brian Frons, Barbara Esensten, James Harmon Brown, Charles Pratt, Jr. and Julie Hanan Carruthers.
In 2013, Little wrote a comedy pilot Kitten Chic about a psychotic fag hag that aired on Sky Living and rejoined the writing team of Hollyoaks.
He rejoined EastEnders in 2013 as part of Dominic Treadwell-Collins' team, receiving acclaim for an episode where Johnny Carter came out to his father Mick, played by Danny Dyer.
From 2022 onward, Little has been involved in the production of Netflix reality shows Young, Famous & African and Dubai Bling.