The southern platform canopy is built out of iron in a neoclassical design from the early years of the railway in Darmstadt.

In addition, a freight link, which is about seven kilometres long, runs from Stockschneise junction (towards Weiterstadt) to Darmstadt-Kranichstein with connections towards Darmstadt Central Station and towards Arheiligen and Frankfurt.

After the Second World War, it changed into a junction station when the original route of the Odenwald railway was dismantled and its trains were diverted to the tracks of the line to Aschaffenburg from the Hauptbahnhof.

The flyover of Frankfurter Straße runs parallel to the alignment of the Darmstadt Nord station building over the tracks; bus and tram services operate over it.

DB Regio has operated Regionalbahn service RB 75 on the Rhine-Main Railway since the summer of 2008 with double-deck sets hauled by Class 143 locomotives.