Darrell Henderson Jr. (born August 19, 1997) is an American professional football running back.

He played college football for the Memphis Tigers, and was selected by the Los Angeles Rams in the third round of the 2019 NFL draft.

As a sophomore in 2017, Henderson played in 12 games with 10 starts and rushed for 1,154 yards on 130 carries with nine touchdowns.

[6] On December 12, 2018, Henderson opted to forgo the remainder of his collegiate career and declared for the 2019 NFL draft.

[7][8] Henderson was selected by the Los Angeles Rams in the third round with the 70th overall pick in the 2019 NFL Draft.

[14] In Week 16, Henderson suffered a high ankle sprain and was placed on injured reserve on December 29, 2020.

He was activated off injured reserve on February 11, 2022 in time for Super Bowl LVI.