He was selected by the Buffalo Bills in the third round of the 1991 NFL draft after playing college football at Pittsburg State University.
[2] He totaled 47 tackles, four interceptions, and ten pass breakups his senior year in 1990, garnering first-team All-MIAA recognition for the second consecutive season.
[2] Wren was selected by the Buffalo Bills in the third round, with the 82nd overall pick, of the 1991 NFL draft.
[4] Wren also missed the entire 1992 season after being placed on the reserve/physically unable to perform list on August 25, 1992.
[4] On August 19, he was traded to the Seattle Seahawks for a 1995 sixth round draft pick.