Darwin Rush James (May 14, 1834 – November 19, 1908) was a U.S. Representative from New York.

He entered the mercantile business in New York City in 1850, became Secretary of the New York Board of Trade and Transportation, and served as Park commissioner of Brooklyn in 1876–1882.

He served as chairman of United States Board of Indian Commissioners in 1890.

He was interred in the City Cemetery, Williamsburg, Massachusetts.

This article incorporates public domain material from the Biographical Directory of the United States Congress