He was born at Segrwyd, near Denbigh, son of Robert Wynn Dolben.
In 1625 he became prebendary of Vaynol, or the golden prebend, in St Asaph Cathedral, a post he held until 1633, just before his death.
He was elected on 18 November and consecrated on 4 March 1632 by Archbishop George Abbot at Lambeth.
In the autumn of the same year he went down to a mortal sickness at the town house of his see in Shoe Lane, Holborn, where he died on 27 November.
He was buried in Hackney parish church, where his monument, containing a half-length statue and a eulogistic description of him, still remains.