David Leigh Donoho (born March 5, 1957) is an American statistician.

[1] His work includes the development of effective methods for the construction of low-dimensional representations for high-dimensional data problems (multiscale geometric analysis), development of wavelets for denoising and compressed sensing.

He has been the Ph.D. advisor of at least 20 doctoral students, including Jianqing Fan and Emmanuel Candès.

In 2001, he won the John von Neumann Prize of the Society for Industrial and Applied Mathematics.

[2] He was elected a SIAM Fellow[8] and a foreign associate of the French Académie des sciences[9] in 2009, and in the same year received an honorary doctorate from the University of Chicago.