In 2015, producer Gail Mutrux adapted the novel into an Oscar-winning film also called The Danish Girl, directed by Tom Hooper and starring Eddie Redmayne and Alicia Vikander.

In 2017 The New York Times named The Danish Girl as one of the "25 books that have shaped LGBTQ literature over the past 20 years.

"[1] In 2017 Ebershoff established the Lili Elbe scholarships for emerging transgender writers in conjunction with the Lambda Literary Foundation.

Kirkus Reviews said that it was "reminiscent of Wallace Stegner's Angle of Repose in scope and ambition", while the Los Angeles Times praised it by saying that "it does that thing all good novels do: it entertains us."

In 2010, the book was made into a television movie of the same name starring Matt Czuchry, Patricia Wettig, and Chyler Leigh.

In September 2020, he published an essay in The Paris Review about editing Supreme Court Justice Ruth Bader Ginsburg Editing Justice Ginsburg Ebershoff has worked as a book editor at Random House for twenty years, starting as a summer intern.

He edited "America's War for the Greater Middle East" by Andrew Bacevich which was longlisted for the 2016 National Book Award.

He edited "Behold the Dreamers" by Imbolo Imbue, winner of the 2017 PEN/Faulkner Award and the 2017 Oprah Book Club selection.

Ebershoff has edited writers David Mitchell, Gary Shteyngart, Adam Johnson, former United States Poet Laureate Billy Collins, Teju Cole, Charles Bock, Jennifer duBois, Nobel Peace Prize-winner Shirin Ebadi, Academy Award-winning actress Diane Keaton, and Pulitzer Prize winners Sonia Nazario, Amy Ellis Nutt, Sebastian Smee, and Robert Massey.