[4][5] NCBI is the home of GenBank,[6] the U.S. node of the International Sequence Database Consortium, and PubMed, one of the most heavily used sites in the world for the search and retrieval of biomedical information.

The internal research program at NCBI included groups led by Stephen Altschul (another BLAST co-author), David Landsman, Eugene Koonin[12] (a prolific author on comparative genomics), and L. Aravind.

Lipman also worked for many years with Dennis A. Benson and others at NCBI on the maintenance and improvement of GenBank, one of the world's largest databases of genome and protein sequence data.

[citation needed] He is also the editor-in-chief for an open-access, peer-reviewed online scientific journal called Biology Direct.

[21] In May 2017, Lipman left his role at the NCBI to join the plant-based meat company Impossible Foods as chief scientific officer.