Chan School of Public Health and professor of biostatistics and computational biology at the Dana–Farber Cancer Institute.

His PhD thesis explored the use of statistics to model harmonies in sound signals and was supervised by David R.

[2][6][7] Irizarry joined the Johns Hopkins Bloomberg School of Public Health in 1998, where his research focused on genomics and computational biology.

[10][14][15] Irizarry is the developer and instructor for the online Data Analysis for Life Sciences course on the Harvard University edX platform; this course enrolls over 30,000 students per year.

2017 Benjamin Franklin Award in Bioinformatics for his promotion of free and open-access materials and methods in the life sciences.