He is the earliest known Jewish composer of polyphonic music of which any has survived.
He worked in banking throughout his life, holding concessions as a moneylender.
[1] The collection is dedicated to his patron, Marquis Alfonso del Vasto, a member of the Gonzaga family, and is dated 25 January 1575.
Published in Venice, the book includes a sonnet praising Sacerdote, by Cavaliere Nuvolone, a member of a Mantuan academy founded by Cesare Gonzaga.
[2][3] As only one part (the quinto) survives, it is impossible to assess fully the stylistic nature of his work, but he appears to have been a competent composer working in the circle of the Mantuan court, where the contributions of Jewish musicians were appreciated, at least during the last third of the 16th century.